ABOUT PREP
Men who have sex with other men
- If you are HIV negative and you take your prep daily as ordered or you are at least taking it four times per week
- Your risk of acquiring HIV is reduced by about 99 percent.
- You have to take your prep at least four days out of the week because if you don't then you are not being protected.
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Heterosexual Men and women
PrEP is an effective way to prevent HIV infection. It is estimated to be 88-90% effective when used recently. However, there is no effectiveness estimate for PrEP when taken daily or consistently among heterosexuals. The effectiveness of oral daily PrEP is highly dependent on adherence, with maximum effectiveness when taking PrEP daily and lower effectiveness when not taken consistently.(Effective HIV Prevention Strategies | HIV Risk and Prevention Estimates | HIV Risk and Prevention | HIV/AIDS | CDC, 2019)
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People who inject drugs
People who inject drugs (PWID) face HIV risks from both injecting and sex behaviors. Studies on the effectiveness of daily PrEP among PWID are limited, but they suggest that PrEP can reduce the risk of HIV acquisition by 74-84% when taken consistently. These estimates are based on tenofovir alone and among a subset of PWID taking PrEP consistently, as verified by directly observed therapy or daily diary plus monthly pill count. The effectiveness of two-drug oral therapy has not been assessed among PWID, but it may be higher. The effectiveness of oral daily PrEP is highly dependent on adherence, with maximum effectiveness when taking PrEP daily and lower effectiveness when missing doses. (Effective HIV Prevention Strategies | HIV Risk and Prevention Estimates | HIV Risk and Prevention | HIV/AIDS | CDC, 2019)
https://www.cdc.gov/hiv/pdf/risk/prep/cdc-hiv-prep-guidelines-2021.pdf
REferences
Effective HIV Prevention Strategies | HIV Risk and Prevention Estimates | HIV Risk and Prevention | HIV/AIDS | CDC. (2019, November 12). Www.cdc.gov. https://www.cdc.gov/hiv/risk/estimates/preventionstrategies.html#anchor_1562942347
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